Tuskegee University Center for Biomedical Research/ RCMI, 2023–2028 “Role of Obesity as a causative factor of breast cancer in African American women”

Research Areas

  • Breast Cancer Biology & Therapeutic
  • Genetics & Epigenetics of Breast Cancer Disparity
  • Spatial Omics & Systems Oncology

Scientific Achievements

  • Race against time: Why TNBC is so aggressive in young African American.
  • Integrating Social Determinants of Health with Breast Cancer database.
  • CereNet: A Cerebellum-Inspired AI Model for Tumor Coordination Analysis.
  • Mapping Immune Checkpoint Dynamics in Spatial Tumor Ecosystems.
  • AI-Driven Integration of Clinical, Molecular, and Social Contexts.
  • Recognized as one of 25 Women Who Shape the State of Alabama.

Funding

RCMI Funding:

  • 5U54MD007585, NIH/NIMHD

Other funding obtained with RCMI support:

  • 1UG3HG013553-01, National Human Genome Research Institute
  • BCRFA

Scientific Advance

African Ancestry–Associated Gene Expression Profiles in Triple-Negative Breast Cancer Underlie Altered Tumor Biology and Clinical Outcome in Women of African Descent
Cancer Discov (2022) 12 (11): 2530–2551.

Obesity Influences the Expression of Key Immunomodulators in Normal Human Breast Tissue, Basal-like Breast Cancer Patients, and Cell Lines Cancers 2022, 14(22), 5599; https://doi.org/10.3390/cancers14225599

The immunopeptidome of colon cancer cells treated with topoisomerase inhibiting drug reveals differential as well as common endogenous protein sampling and display of MHC I-associated peptides. Molecular & Cellular Oncology, https://doi.org/10.1080/23723556.2025.2471640

Methods and compositions for the identification of epithelial to mesenchymal breast cancer US Patent number 11624748

NIH/NIMHD #U54MD007585
Toggle Navigation