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News from the Network

April 21, 2022 / Clark Atlanta University

Purification and Identification of Natural Inhibitors of Protein Arginine Methyltransferases from Plants

Protein arginine methyltransferase (PRMT) enzymes catalyze posttranslational modifications of target proteins and are often upregulated in human cancers. In this study, we purified two chemical…

November 12, 2021 / Clark Atlanta University

Overcoming prostate cancer drug resistance with a novel organosilicon small molecule. Neoplasia, 23:1261-1274, 2021.

A major challenge to the treatment of advanced prostate cancer (PCa) is the development of resistance to androgen-deprivation therapy (ADT) and chemotherapy…

August 25, 2021 / Clark Atlanta University

Epithelial protein lost in neoplasm (EPLIN) and prostate cancer: lessons learned from the ARCaP model. American Journal of Clinical and Experimental Urology, 9:264-276, 2021.

Confucius said, “Good tools are prerequisite to the successful execution of a job”. Among his many groundbreaking achievements, Dr. Leland W. K. Chung established several… Continue Reading

May 8, 2021 / Clark Atlanta University

Pharmacological inhibition of noncanonical EED-EZH2 signaling overcomes chemoresistance in prostate cancer Theranostics, 11:6873-6890, 2021

Prostate cancer (PCa) is the most commonly diagnosed cancer and the second leading cause of cancer death among American men 1. As the first-line chemotherapy for… Continue Reading

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Research Centers in Minority Institutions (RCMI) Coordinating Center is supported by the National Institute on Minority Health and Health Disparities, National Institutes of Health (NIH), through Grant Number U24MD015970. The contents of this site are solely the responsibility of the authors and do not necessarily represent the official views of the NIH.

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Pilot Projects Program Funding Cycle is Now Open

The RCMI Coordinating Center Clinical Research Pilot Projects Program is intended to provide funding, on a competitive basis, for hypothesis-driven clinical research projects led by inter-institutional collaborative teams of multiple principal investigators (MPI) from two or more RCMI U54 Centers, along with at least one Mentor and at least one Collaborator from RCMI and/or non-RCMI grantee institutions. View Application Details.